Scroll To Top


Landrum B. Shettles, M.D., Ph.D., F.A.C.O.G., F.A.C.S., F.R.S.H.

landrum-b-shettles, M.D.


1930 | 1940 | 1950 | 1960 | 1970 | 1980 | 1990 | 2000



Shettles, L. B. and Mast, S. 0.  Response to Light in Peranema Trichophorum with Special Reference to Dark Adaptation and Light Adaptation. Anat. Rec. 67:41-42, 1936

Shettles, L. B. Response to Light in Peranema Trichophorum with Special Reference to Dark Adaptation and Light Adaptation. Jour. Exp. Zool. 77:215-249, 1937.

Shettles, L. B. Effect of Ultraviolet Light and X-Rays on Peranema Trichophorum. Jour. Cell and Comp, Physiology, 12:263-272, 1938.

Shettles, L. B.  Possibilities of Rainbow Trout and Large Mouthed Bass in the Middle Rio Grande Conservancy Drains. "Trans. 3rd North Amer. Wildlife Conference, 1933, Ainer, Wildlife Institute Investment Bldg., Washington, D. C, 365-367.

Shettles, L. B.  Effect of Light and Darkness on Recovery in Peranema Trichophorum after Response to Light.  Anat. Rec, 72:81-82, 1938.

Shettles, L. B. The Relation Between Salts, Hydrogen-ion Concentration and Sensitivity to Light in Peranema Trichophorum. Jour. Exp. Zool., 81:473-477, 1939.

Hellman, L. M. and Shettles, L. B.  Factors Influencing Plasma Prothrombin in the Newborn Infant.  I.  Prematurity and Vitamin K.  Bull. Johns Hopkins Hospital.  65:138-141, 1939.

Shettles, L. B.  Studies on Human Spermatozoa.  I. Respiration of Human Spermatozoa. Anat. Rec, 75:145, 1939.

Shettles, L. B.  Studies on Human Spermatozoa.  II.. Response of Human Spermatozoa to Various Gases. Anat. Rec, 75:145, 1939

Shettles, L. B,  Studies on Human Spermatozoa.  III. Factors Influencing the Resistance of Human Spermatozoa to Very Low Temperatures. Anat. Rec, 75:146, 1939.



Shettles, L. B.  The Respiration of Human Spermatozoa and Their Response to Various Gases and Low Temperatures.  Amer Jour Physiol, 128:408-415, 1940.

Shettles, L. B. and A. F. Guttmacher.  Normal and Abnormal Variations in Human Cervical Mucus. Amer Jour Physiol, 129:462-463, 1940.

Shettles, L. B. and Guttmacher, A. F.  Cyclic Changes in Cervical Mucus and its Practical Importance.  Human Fertility, 5:4-9, 1940.

Shettles, L. B.  Resistance of Human Spermatozoa In Vitro to Sulfanilamide and Sulfapyridine.  Proc, Soc, Exp. Biol, and Med, 44:392-393, 1940.

Shettles, L. B., Lamar, J. K. and Delfs, E.  Cyclic Penetrability of Human Cervical Mucus to Spermatozoa In Vitro.  Amer. Jour, Physiol., 129:234-241, 1940.

Hellman, L. M., Moore, W. J., and Shettles, L. B.  Factors Influencing Plasma Prothrombin in the Newborn Infant. III.  Study of the Vitamin K Activity of Various Napthohydroquinone Derivatives.  Bull. Johns Hopkins Hospital, 66:379-389, 1940.

Shettles, L. B.  Carbon Dioxide Tension and its Relation to Quiescence of Spermatozoa In Vivo.  Proc Soc Exp Biol and Med, 45:318-322, 1940.

Shettles, L. B.  A Method for Studying the Penetravility of Human Cervical Mucus by Spermatozoa. Anat, Rec, 78:148, 1940.

Hellman, L. M.  Shettles, L. B. and Eastman, N. J. Vitamin K in Obstetrics. Amer Jour Obstet and Gynecology.  40:844-853, 1940.

Maumenee, A. E., Hellman, L. M. and Shettles, L. B.  Factors Influencing Plasma Prothrombin in the Newborn Infant. IV.  The Effect of Antenatal Administration of Vitamin K on the Incidence of Retinal Hemorrhage in the New born. Bull. Johns Hopkins Hospital, 68:158-168, 1941.

Holt, L. E., Jr., Albanese, A. A. and Shettles, L. B. Studies of Experimental Amino Acid Deficiency in Man.  I. Nitrogen Balance.  Proc. Fed. Amer. Soc, Exp. Biol., 1:116-117, 1942.

Shettles, L. B. and Hellman, L. M. The Prophylactic Use of Vitamin K in Obstetrics. Southern Medical Journal, 35:289-293, 1942.

Shettles, L. B. and Jones, G. E. S. The Effect of Thyroidectomy on Spermatogenesis in the Adult Guinea Pig. Anat. Rec. 84:531, 1942.

Shettles, L. B., Hellman, L. M. and Stran, H. A Quantitative Method for the Determination of Sodium Pentothal in Blood. Jour. BioL Chera, 148:293-297, 1943.

Shettles, L. B. The Effect of Low Oxygen Tension Upon Reproduction In the Male Guinea Pig. Anat. Rec, 87:472, 1943.

Shettles, L. B. The Survival of Human Spermatozoa in Solutions of Penicillin. Anat Rec, 89:28, 1944.

Shettles, L. B., Hellman, L. M., Manahan, C. P. and Eastman, N. J. Sodium Pentothal Anesthesia in Obstetrics. Amer. Jour. Obstet. and Gynecol,, 48:851-860, 1944.

Shettles, L. B. The Relation of Nutrition to Spermatogenesis. Proc:  Third Annual Conference on Sperm Biology, National Committee on Maternal Health, New York, 1944.

Shettles, L. B. Effects of Low Oxygen Tension on Fertility in Adult Male Guinea Pigs. Federation Proceedings, 6:200, 1947.

Shettles, L. B. and Dische, Z. The composition of Polysaccharides of Human Cervical Mucus. Federation Proceedings, 7:114, 1948.

Shettles, L. B., Delfa, D. and Hellman, L. M. Factors Influencing Plasma Prothrombin in the Newborn Infant.  II. Antepartum and Neonatal Ingestion of Vitamin K Concentrate. Bull Johns Hopkins Hospital, 65:419-426, 1939.

Atkinson, W. B., Shettles, L. B. and Engle, E. T. Histochemical Studies on the Secretion of Mucus by the Human Endocervix. Anat Rec, 100:5, 1948.  Ibid. Amer Jour Obstet and Gynecol, 56:712-716, 1948.



Zamenhof, S., Shettles, L. B. and Chargaff, E. Human DNA Isolation From Human Sperm. Nature, 165:756, 1950.

Dische, Z and Shettles. A Specific Color Reaction of Methylpentoses and a Spectrophotometry Micromethod For Their Determina­tion. Jour Biol Chem, 175:595-603, 1948.

Dische, Z. and Shettles, L. B. A New Spectrophotometric Test for the Detection of Methylpentose. Jour Biol Chem, 192:579-582, 1951.

Shettles, L. B. The Polysaccharide Composition of Human Cervical Mucus.  Fertility and Sterility, 2:361-368, 1951.

Shettles, L. B. and Dische, Z and Osnos, M. Neutral Mucopoly­saccharide of the Human Cervical Mucus. Jour Biol Chem. 192:589-593, 1951.

Shettles, L. B. Der Zervikalzyklus Beim Menschen, Geburtshilfe und Frauenheilkunde, 12:1-10, 1952.

Robinson, D. and Shettles, L. B.  The Use of Diethylstilbestrol in Threatened Abortion, Amer Jour Obstet and Gynecol. 63:1330-1333, 1952.

Shettles, L. B. Observations in Obstetrics and Gynecology in the British Isles and Western Europe, 0 N R L0105-52 Technical Office of Naval Reserve Report, London, 1952.

Shettles, L. B. Observations on Human Follicular and Tubal Ova. Federation Proceedings.  12:131, 1953.

Shettles, L. B. Observations on Human Follicular and Tubal Ova. V" Amer Jour Obstet and Gynecol, 66:233-247, 1953.

Shettles, L. B. and von Kaulla, K. N. The Relationship Between Human Seminal Fluid and the Fibrinolytic System. Proc Soc Exp Biol and Med, 83:692-694, 1953.

Shettles, L. B. Studies on Living Human Ova. The New York Academy of Seiences, Section of Biology Presented on November 8, 1954.

Shettles, L. B. and von Kaulla.  Beitrag sur Kenntnis des Proteolytischen Fermentsystems im Menschlichen Spermaplasma, Mucus Cervical is, Tubarschleimhaut und Liquor Folliculi. Klinische Wodhenschrift, 15:468-472, 1954.

Shettles, L. B. Die Klinische Bedsutung der zyklischen Verand-erungen der Mukosa der Cervix uteri und deren Absonder-ungen. Klinische Fortschritte Gynakoligie, edited by Prof. T. Antoine, Urban und Schwarzenberg, Vienna und Innsbruck, pp 264-277, 1954.

Shelttles, L. B. Observations on Maturation, Fertilization and Cleavage of Human Follicular and Tubal Ova. Excerpta Medica. 7:320-321, 1954.

Shettles, L. B. Chorionepithelioma Following a Full Term Pregnancy, Amer Jour Obstet and Gynecol. 69:869, 1955„

Shettles, L. B. Further Observations on Living Human Oocytes and Ova. Amer Jour Obstet and Gynecol. 69:365, 1955.

Shettles, L. B. A Morula Stage of Human Ovum Developed In Vitro. Fertility and Sterility, 6:287, 1955.

Shettles, L. B. Studies on Living Human Ova. Bull New York Academy of Medicine, 31:153, 1955: Trans New York Academy of Sciences, 17:99, 1955.

Shettles, L. B. Observations on Maturation, Fertilization and Cleavage of Human Follicular and Tubal Ova. From: Tendances Actuelles en Gynecologie et Obstetrique, Georg & Cie. S. A., Editeurs, Geneve, 1955

Shettles, L. B. and Flick, F. and Taylor, H. C. Clearance of Radioactive Sodium from the Cervix. Amer Jour Obstet and Gynecol, 71:1176-1181, June 1956.

Shettles, L. B. and von Kaulla, K. N. Thromboplastic Activity of Human Cervical Mucus and Ovarian Follicular and Seminal Fluids. Fertil and Sterility.  7:166-169, March - April, 1956.

Shettles, L. B. Nuclear Morphology of Cells in Human Amniotic Fluid in Relation to Sex of Infant. Amer Jour Obstet and Gynec. 71:834-838, April 1956.

Shettles, L. B. A New and Improved Method for Delivery of the Placenta.  Amer Jour Obstet and Gynec.  72:683-684, September 1956.

Shettles, L. B. Diagnosis of Sex Before Birth.  Bull Sloane Hospital for Women.  11:69-72, September 1956.

Shettles, L. B. Erstmalig Gelungene Entwicklung des Menschlichen Ovums bis zum Morulastadium In Vitro.  Therapeutische Berichte.  28:186-187; 1956.

Shettles, L. B. Morula Stage of Human Ova Developed In Vitro. Clinical Excerpts, Vol XVIII, No. 4, pp 92-93, 1956.

Shettles, L. B. Intrafollicular Cleavage of Human Ovum. Nature, 178:1131, November 1956.

Shettles, L. B. Sex of Infant in Relation to Nuclear Morphol­ogy of Cells in Human Amniotic Fluid.  Federation Proceedings, 15:170, 1956.

Shettles, L. B. The Ovum in Infertility, Abortion and Develop­mental Anomaly.  Fertility and Sterility, 7:561-572, November - December 1956.

Shettles, L. B. Studying the Activity of Human Spermatozoa about the Ovum In Vitro.  Research Film 2:4, December 1956.

Shettles, L. B. Parthenogenetic Cleavage of the Human Ovum. Bull Sloane Hospital for Women III: 59-61, June 1957.

Shettles, L. B. The Living Human Ovum.  Obstet and Gynec 10: 359-365, October 1957.

Shettles, L. B. and Freda, V. J.  Polynuclear Oocytes and Polyovular Follicles in Stein-Leventhal Syndrome. Bull Sloane Hospital for Women.  4:71-75, Fall 1958.

Shettles, L. B. Corona Radiata Cells and Zona Pellucida of Living Human Ova.  Fertility and Sterility, 9:2, March - April 1958.

Shettles, L. B. The Living Human Ovum. Amer Jour Obstet and Gynec, 76:398-406, August 1958.

Shettles, L. B. Biological Sex Differences with Special Reference to Disease, Resistance and Longevity. Jour of Obstet and Gynec of British Empire, 65:288-294, April 1958.

Shettles, L. B. The Nourishment of the Human Ovum. Bull Sloane Hospital for Women.  4:34-38, Summer 1958.

Shettles, L. B.  Die Lebende Menschliche Eizelle. Sonderdruck aus Archiv fur Gynakologie Bd 193:287-284, 1958.

Shettles, L. B. Cervical Factors in Reproduction. Obstet and Gynec. 14:635-636, November 1959.

Corscaden, J. A. and Shettles, L. B. Hydadiform Mole and Chorio Carcinoma.  Bull Sloane Hospital for Women.  5:41, 1959.



Shettles, L. B. Hourly Variation in Onset of Labor and Rupture of Membranes. Amer Jour Obstet and Gynec, 79:177-179, January 1960.

Shettles, L. B. Ovum Humanum.  Verlag von Urban und Schwarzenberg. Munich, 1960.

Shettles, L. B. The Relation of Dietary Deficiencies to Male Fertility. Fertility and Sterility, 2:88-99, January - February 1960.

Shettles, L. B. Nuclear Morphology of Human Spermatozoa. Obstet and Gynec, 16:10-14, July 1960.

Shettles, L. B. Observations on Human Spermatozoa. Bull Sloane Hospital for Women.  6:48-54, Summer 1960.

Shettles, L. B. X and Y Spermatozoa. Nature, Vol 187, No. 4733, pp 254-255, July 16, 1960.

Shettles, L. B.  Nuclear Structure of Human Spermatozoa. Nature. Vol. 188, No. 4754, pp 918-919, December 1960.

Shettles, L. B. Ovum Humanum. Bull  Sloane Hospital for Women, VI:No. 4, Winter 1960.

Shettles, L. B. Differences in Human Spermatozoa. Fertility and Sterility, 12:20-24, January - February 1961.

Shettles, L. B. After Office Hours.  Conception and Birth Sex Ratios. A Review.  Obstet and Gyhec, 18:121-130, July 1961.

Shettles, L. B. The Normal Human Endometrium.  The Endometrium and Implantation.  Ed.  Schraidt-Matthiesen, Gottingen.  1961

Shettles, L. B. Sperm Shape and Sex Ratios. Transactions of the Annual Meeting of the Society of the Alumni of the Sloane Hospital for Women. (See Reprint No. 84, p 74) 1961.

Shettles, L„ B. Sperm Morphology and Sex Ratios. Journal of Urology, Vol 86, No. 4, October 1961.

Shettles, L. B. Human Sperm. Fertility and Sterility. Vol 12, No. 6, November - December 1961.  (By The American Society for the Study of Sterility.

Shettles, L. B. Human Spermatozoan Types. Gynaecologia, 152: 154-162.  1961.

Shettles, L. B. Endometrium und Nidation. H. Schmidt-Matthiesen, Gottingen. Georg Thieme Verlag, Stuttgart, 1962

Shettles, L. B. Normal and Abnormal Ovulation in the Ovary. International Academy of Pathology Monograph No. 3. Ch 8, Baltimore, The Williams & Wilkins Company, p 128-142.  1962.

Shettles, L. B. Human Spermatozoan Populations. International Journal of Fertility.  7:175, April - June, 1962.

Shettles, L. B. Human Fertilization.  Obstet and Gynec, 20: 750, December 1962.

Shettles, L. B. Die Befruchtung Beim Menschen.  Sonderdruck aus Archiv fur Gynakologie Bd. 198.  (34.  Verhand-lungsbericht der Deutschen Gessellschaft fur Gyn­akologie in Hamburg. 1962.

Shettles, L. B. Recurrent Theca Lutein Cysts. Obstet and Gynec. 21:339, March 1963.

Shettles, L. B. The Zona Pellucida with Special Reference to Early Human Development.  Gynaecologia, 155:145, 1963.

Shettles, L. B. Ovum Humanum. Einbettung und Ansiedlung des Menschlichen Embryos.  1963.

Shettles, L. B. The Great Preponderance of Human Males Con­ceived. Amer Jour Obst and Gynec, 89:130, May 1964.

Shettles, L. B. Die Befruchtung Beim Menschen. Sonderdruck aus Almanach fur die Frauenheilkunde. Seite 9 bis 14 p 1.  1964.

Shettles, L. B. In The Beginning. Bull Sloane Hospital for Women. 10:246, Winter, 1964.

Shettles, L. B. The Endometrium and Implantation.  Ed.  H. Schmidt Mattiese.  McGraw Hill, 1968.

Shettles, L. B. Das Menschliche Ei und Seine Befruchtung. Gynakologie u Geburtshilfe, p 545. Georg Thieme, Stuttgart, Germany, 1969.

Shettles, L. B. Die Physiologie der Konzeption. Gynakologie u Geburtshilfe, pp 55-64, Georg Thieme, Stuttgart, Germany, 1969

Shettles, L. B. Cervix Factor. The Journal of Reproductive Medicine, 3:43-46, 1969.



Shettles, L. B. Factors Influencing Sex Ratios. International Journal of Gynecology and Obstetrics, 8:643-647, 1970.

Shettles, L. B. Human Fertilization and Development From the Inner Cell Mass.  Scientific Foundations of Obstetrics and Gynecology. (American College Obstetrics and Gynecology)  William Heinemann and Sons, London and F. A. Davis, Philadelphia, Pa. USA 1970.

Shettles, L. B. and Rugh, Robert. From Conception to Birth: The Drama of Life's Beginnings. Harper and Rowe, 1971.

Shettles, L. B. and Rorvik, David. Your Baby's Sex:  Now You Can Choose.  Dodd Meade & Co.  1971.

Shettles, L. B, Human Blastocyst Grown In Vitro In Ovulation Cervical Mucus.  Nature, 229:343, 1971.

Shettles, L. B. Quinacrine Used to Determine the Sex of a Fetus. Nature, 229:52, 1971.

Shettles, L. B.  Use of the Y Chromosome in Prenatal Sex Determin­ation.  Nature.  Vol 230, No. 5288, pp 52-53, 1971.

Shettles, L. B. Fertilization and Early Development From the Inner Cell Mass.  Scientific Foundations of Obstetrics and Gynaecology.  Ed:  Philipp, Barnes & Newton, London, and William Heinemann and Sons, London and F. A. Davis, Philadelphia, Pa. USA 1971.

Shettles, L. B. Choosing The Sex Of Your Infant. Human Sexuality. September 1972.

Shettles, L. B. The Criteria of Human Fertilization In Vitro. Presented at Sectional Meeting of The American College of Surgeons in Montreal Canada, 1972.

Shettles, L. B. Time of Conception and Sex of Infant. Drug Therapy. April 1973.

Shettles, L. B.  In Vitro Fertilization of Human Ova and Blastocyst Transfer. An Invitational Symposium: The Journal of Reproductive Medicine, 1973.

Shettles, L. B. The Human Hydronaut. Obstetrics and Gynecology. Vol 42, No. 3, September 1973.

Shettles, L. B. Cervical Milieu and Conception. Correspondence: American Journal Obstetrics and Gynecology.

Shettles, L. B.  In Vitro Fertilization with Embryo Transfer inUtero. Translated by Prof. Botella-Llusia, University of Madrid.  Acta Ginecologia, 1975.

Shettles, L. B. Potassium Iodide Can Increase Conception Odds. Drug Therapy, May 1976.

Shettles, L. B.  Separation of X & Y Spermatozoa. The Journal of Urology.  116:462-463, October 1976.

Shettles, L. B. Sex Selection Infertility. Wayne Decker, Editor. 2:81, 1976

Shettles, L. B. and Rorvik, David.  Choose Your Baby's Sex. Dodd, Mead & Co. New York. 1977.

Shettles, L. B. Man's  Sojourn In Utero. 8:19 New England Journal of Medicine, 1978. Sept. 18

Shettles, L. B. Sleeping Habits and Placental Location. The Female Patient, May 1978.

Shettles, L. B. Sleeping Posture Governs  Implantation Site of Fertilized Ovum. The Female Patient,  Ed. Hugh Barber, 1978.

Shettles, L. B. Diploid nuclear replacement  in mature human ova with cleavage. Amer.Jour.Obstet-Gynee.   133:222, 1978.

Shettles, L. B. Ova harvest with in vivo fertilization. Amer. Jour. Obstet. Gynec. 133:845, 1979.



Shettles, L. B. Unexpected fertiliization sites, Female Patient, 5:97, 1980.

Shettles, L. B. Further observations on human oocytes in vitro, Int'l. J . Fertility,25: 1980

Shettles, L. B. Ethanol and premature infants.Amer.Jour.Obs.Gyn. 140:351, 1981.

Shettles, L. B. Recurrent theca lutein cysts. Female Patient, 7:36/71, 1982.

Shettles, L. B. Preponderance of in vitro births female. Amer.Jour.Obstet-Gynec., Sept. 1983.

Shettles, L. B. David M. Rorvik. The Rites Of Life: The Scientific Evidence of Life Before Birth. Zondervan Press. Grand Rapids, Mich. 1983.

Shettles, L. B. & David M. Rorvik How To Choose The Sex Of Your Baby. Doubleday, NYC, 1984

Shettles, L. B. Adopting A Conceptus. Medical Tribune, April 25,  p. 9, 1984.

Shettles, L. B. History of Chorionic Villi Sampling. Contempory OB/GYN, April, 1984

Shettles, L. B. An Hereditary Composite. Medical Tribune, Aug. 7, 1985

Shettles, L. B. Concerning Sex Selection. OB/GYN World. Hay 1987

Shettles, L. B. Ova  harvest with fertilization  following intrafallopian transfer. Infertility 10:51, 1987.

Shettles, L. B. Novelty of GIFT. Contemporary OB/GYN, January, 1988.

Shettles, L. B. Ovulation in relation to cervical canal diameter. Amer. Jour.
Obset. & Gynec. Vol.  159 No. 6. Deb. 1988

Shettles, L. B. Diurnal rhythmicity in labor onset end membrane rupture.
Female Patient, April,  1988 p. 16

Shettles, L. B. and David Rorvik.  How To Choose The Sex Of Your Infant. Revised Edition. Doubleday,  NYC, March,  1989.



Shettles, L. B. Etiology of discordant twins. Contemporary OB/GYN, p.  120, August 1990.

Shettles, L. B. How sperm commence movement and  their isolation for in vitro fertilization and sex selection Amer. Jour.Obstet. & Gynecol p. 270, July 1990.

Shettles, L.B. Tubal embryo successfully transferred in utero. Amer.  Jour. Obstet & Gynecol. p.2026, Dec. 1990.

Shettles, L. B. Carbon dioxide and sperm motility. Fertility & Sterility March 1994, P.576.

Shettles, L. B. Fraternal twin conceptions. Contemporary OB/GYN, May 1994 p.120.

Shettles, L. B. and David Rorvik. How to Choose your Baby’s Sex,. Doubleday, NYC, Jan 1997



Shettles, L. B. and David Rorvik. How to Choose The Sex Of Your Baby. Broadway Books, NY, 2006

An ingenious mind... superb technical ability.

—Dr. Alan F. Guttmacher, former national president
of Planned Parenthood-World Population